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26 cases of stage D prostatic carcinoma admitted to Dept. of Urology during the period from August 1, 1970 through July 31, 1984 were observed clinically. 1. 26 cases (43.3%) among 60 cases of prostatic carcinoma belonged to stage D at the time of diagnosis. 2. The presenting symptoms showed prostatic obstruction in 21 cases, gross hematuria in 8 cases and lumbago in 2 cases. 3. Serum acid phosphatase activity was elevated in 12 cases (46.2%). Serum alkaline phosphatase activity was elevated in 8 cases (30.8%), 6 cases of whom had osseous metastases. 4. 25 cases revealed adenocarcinoma of the prostate and 1 case revealed squamous cell carcinoma. On the pathological examination, 13 cases were poorly differentiated, 9 cases were intermediate range and 2 cases were well differentiated adenocarcinoma. 5. Orchiectomy was done in 23 cases immediately following biopsy and D. E. S. therapy was done in 7 cases with radiation therapy in 1 case. 6. 15 cases were followed up for more than 1 year, revealing survival rates 73.3% in 1 year, 66.7 % in 2 years and 60% in 3 years.
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